Previous and recent studies have been conducted throughout the world examining the antiviral antiviral properties of medicinal mushrooms against the influenza viruses. There has been an urgent search for antiviral compounds due to the global pandemic, COVID-19. It has been reported that medical mushrooms contain bioactive compounds such as polysaccharides, terpenes, proteins, melanins, and many more that demonstrate an antiviral effect. Research found at the State Research Center of Virology and Biotechnology Vector in Russia showed the results of collected research of a variety of pathogenic viruses. Their investigations found that the chaga mushroom or Inonotus obliquus demonstrated the widest range of antiviral activity.