Vitamin D is a fat-soluble vitamin that is an important key steroid hormone that regulates calcium homeostasis. It is most often found in food and sunlight exposure; the significant source being sunlight because the UV rays from the sun trigger vitamin D synthesis in the skin. There are different forms of vitamin D including D2 (Ergocalciferol) and D3 (Cholecaliferol). Comparing these two, vitamin D3 is the preferred form for clinical and therapeutic applications due to its more active biological half-life. Vitamin D absorption works by converting the vitamin produced in the skin or consumed in food, to a pre-hormone, to the kidneys, to then form the physicologically active form of vitamin D. It sends a signal to the intestines to increase absorption of calcium and phosphorus—the major functions of vitamin D. Because of the vitamin D, calcium helps build and strengthen the bone. The lack of vitamin D may enable the bones to become brittle, thin, or misshapen. In addition, vitamin D deficiency is linked with a number of chronic diseases including cancer, type 1 diabetes, multiple sclerosis, high blood pressure, heart disease, and schizophrenia. As for the composition of the supplementation of vitamin D, the pharmaceutical composition adapted for oral delivery consists of at least 20,000 IU of vitamin D, a lipid-based carrier that regulates vitamin D, and an outer layer comprising of a non-animal derived polymer.