Aloe Vera: Natural Sources of Antioxidants – A Review
MARZANNA HĘŚ, KRZYSZTOF DZIEDZIC, DANUTA GÓRECKA, ANNA JĘDRUSEK GOLIŃSKA, AND ELŻBIETA GUJSKA
Studies have proved that the components of Aloe vera have an anti-inflammatory effect, supports lipids, and antioxidants. The anti-inflammatory properties found can help maintain a normal, healthy body weight, normal sugar and cholesterol levels, and boost carbohydrate metabolism. The antioxidants can increase food shelf-life and nutritional value of food, which is critical to prevent oxidation happening to the food. Because of the high content of antioxidant vitamins found in the plant like vitamins A, C, E, and B12, enables Aloe vera a source of safe and effective antioxidant additives that reduce lipid corrosion. The medical uses of the plant include: wound healing, screening out radiation, reversing aging of the skin and body, helps boost the immune system, treats frostbite and psoriasis, helps to treat tissue burns, and can prevent damage to the liver. It is an anti-viral, anti-tumor, anti-bacterial, anti-diabetic, anti inflammatory, and contains laxative properties. Foods containing natural properties have become highly favored. The use of plant extracts as antioxidants have been gaining popularity by consumers because food containing natural materials are known to be safe.
Pharmacological Update Properties of Aloe Vera and its major constituents
Marta Sánchez, Elena González-Burgos, Irene Iglesias, and M. Pilar Gómez Serranillos*
Because of Aloe vera’s antimicrobial, anti-inflammatory, and wound healing properties, it has been used to treat digestive problems and skin injuries. However, new recent pharmacological data has shown to have other therapeutic properties including anticancer, anti diabetic, antioxidant, and cholesterol-lowering agents. Clinical trials have been conducted and most recent are in vitro and in vivo. A greater number of clinical trials have been encouraged to test Aloe vera’s main compounds, specifically on cancer, diabetes, and bone protection. The plant contains more than 75 different compounds including vitamins, minerals, enzymes, sugars, fatty acids, hormones, and others. Among these compounds, the most major active and researched focused on are aloin, aloesin, amodin, aloe-emodin, and acemannan. These compounds aid skin protection, digestive diseases protection, anti-inflammatory activity, bone protection, heart disease protection, antimicrobial activity, prebiotic activity, and treating reproductive health care problems.
Ultrasound meditated accelerated Anti-influenza activity of Aloe vera
Enkhtaivan Gansukh, Judy Gopal, Diby Paul, Manikandan Muthu, Doo-Hwan Kim, Jae-Wook Oh, and Sechul Chun
Aloe vera is a well-known and commercialized antimicrobial plant used in beauty products, herbal medicines, and laxatives; however, Aloe vera also has antiviral activity. In most recent works, a study was conducted employing a 5 minute ultrasound for the effective removal of the compounds, aloin and aloe-emodin, from water. The compounds were tested for their anti influenza activity, and the results demonstrated that the removal of the compounds allowed the water extracts to show excellent for anti-influenza activity. Comparing the Methanol extracts and the water extracts, researchers proved that the water extracts demonstrated zero cell toxicity whereas the methanol extracts have shown high levels of cell toxicity. The removals of the bioactive chemicals found in Aloe vera have been proven to be of vital importance to have access to all active physiological and pharmaceutical properties.
The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Davood Hekmatpou, PhD, Fatemeh Mehrabi, Kobra Rahzani, PhD, and Atefeh Aminiyan, PhD
Clinical trials were efficiently reviewed aimed to study the effect of Aloe vera on the healing and prevention of skin wounds. Researchers showed that Aloe vera has been used to prevent skin ulcers and to treat genital herpes, psoriasis, burn wounds, post surgical wounds, cracked nipples, and other chronic wounds. In total, 57 articles were studied: 41 studies on
human subjects;16 studied removed due to animal subjects; and 18 studies excluded due to lack of access to full texts, lack of transparency of statistical results, and sample sizes having less than 30 cases. As the result, 23 trails were evaluated. The trails conducted included Aloe vera gel, cream, and byproducts from a control group with placebo and comparisons with other treatments. Data shows that Aloe vera gel can also change the makeup of collagen, increase the flexibility, and reduce the fragility of the skin thereby improving wound healing. The positive effects of more studies have shown aloe vera treat other wounds like mouth sores, ulcers, diabetes, and bedsores. The results from the research demonstrated that the application of aloe vera can retain skin moisture and integrity of the skin.
Aloe vera: A review of toxicity and adverse clinical effects
Xiaoqing Guo and Nan Mei
Aloe vera is used as a dietary supplement in food and as an ingredient is cosmetic products. Because it has has widespread human exposure, there has been safety concerns due to its potential toxic and carcinogenic activities. Data shows that the ingestion Aloe vera’s chemical preparations is linked with kidney failure, diarrhea, potassium deficiency, discoloration of the large intestine, skin irritation, and hypersensitive reactions. In a research study, there was clear evidence of cancer potential activity in rats. Adverse clinical effects Aloe vera have been updated on information on the exposure to toxins including cell toxicity, genetic toxicity, and tumor, cancer potential in animals and risk in humans.
9 Healthy Benefits of Drinking Aloe Vera Juice
Katherine Marengo LDN, R.D
Aloe vera has been commonly used to treat sunburns, but drinking the juice can provide other health benefits. Aloe juice is a way to prevent and treat dehydration by helping the body detox. It provides a way to flush out impurities of the blood and urine thereby keeping the kidneys and liver function healthy. Drinking aloe juice increases the water content in the intestines which can relieve constipation, helping pass stool normally. Because of the hydration benefit, it may reduce acne in the skin because of the rich source of vitamins and antioxidants; and it has helped improved skin conditions like dermatitis and psoriasis. It contains important vitamins like A, B, C, E, B-12, and folic acid that provide a nutritious boost and can be a key factor is preventing diseases. Relief can be provided to heartburn attacks, help control acid in the stomach, and fighting off stomach ulcers. Aloe vera juice can combat irritation of the stomach and intestines because of the supply of enzymes that are known to help the breakdown of fats and sugars. The plant juice is also used for a number of beauty hacks including makeup primer, makeup remover, sunburn soother, lightweight moisturizers, and scalp irritation. A study conducted using concentrations of purified aloe vera proved to have no adverse effects from the juice.
Aloe Vera Juice: The Gut-Friendly, Detoxifying Drink Christine Ruggeri, CHHC
The three layers of aloe vera, crushed, ground, and filtered, have been used from fighting off infections, improving health of the skin to aiding detoxification and digestive problems. The juice has become a popular way of boosting hydration and nutrition of the body. The 75 organic compounds of the plant leaf including vitamins and minerals have been proven to be beneficial
for the body. The benefits of the detoxifying drink include it is rich in nutrients, promotes digestive health, supports skin health, increases immune function, improves detoxification, and promotes dental health. To get the full benefits of aloe juice, consumers will want to opt for a purified, organic tested product. The only risk of the juice is digestive issues like diarrhea if too much of the juice has entered the body.
Evaluation of the Nutritional and Metabolic Effects of Aloe Vera Meika Foster, Duncan Hunter, and Samir Samman
The use of Aloe vera has been used for traditional use. In other cultures like Indian, Chinese, Mexican American, it is used as a treatment for type 2 diabetes, high blood pressure, fungal diseases, constipation, skin diseases, worm infestations, stomach pains, and infections. In modern society, it is used in the pharmaceutical, cosmetic, and food industries. The usage of Aloe vera for therapeutic claims cover a wide range of conditions. Clinical trials have begun to increase exploring the effectiveness. Researchers tested the benefits of applying Aloe vera topically, resulting in benefits in skin conditions and wound healing, including burn injuries, surgical wounds, dermatitis, psoriasis, and tissue swelling of the mouth. For oral applications of Aloe vera, researchers determined it can be used as a laxative, treating diabetes, cancer that spreads, and inflammation of the stomach and ulcers.
Aloe Vera: A Systematic Review of its Clinical Effectiveness B K Vogler and E Ernst
Aloe vera is used for treating many conditions. To determine the clinical effectiveness of Aloe vera, four independent literature searches were conducted. As the result, ten studies were included. Researchers suggested that orally administrating Aloe Vera can be a useful addition for lowering glucose in the blood in diabetics and reducing blood lipid levels for patients with abnormally high levels of fats in the body. It was determined that applying Aloe vera topically is not effective in preventing radiation-induced injuries; however, it can be effective for skin psoriasis and genital herpes. At present time, even though the results are encouraging, clinical effectiveness of orally or topically applying Aloe vera has not been clarified sufficiently.
Aloe Polysacchardides Inhibit Influenza A Virus Infection—A Promising Natural Anti-Flu Drug
Zhenhong Sun, Cuilian Yu, Wei Wang, Guangfu Yu, Tingting Zhang, Lin Zhang, Jiguo Zhang and Kai Wei
The Influenza A virus causes annual epidemics, occurring pandemics, acute respiratory distress syndrome, and seriously threatens human health Aloe polysaccharides or APS, an extraction from the Aloe vera plant leaves, have promising effects on the therapy of virus infection. Researchers conducted an in vitro test, determining that APS could restrain the duplication of the subtype of influenza virus, H1N1. The test revealed that APS was directing interacting with the virus particles. In the demonstration on mice, the H1N1 virus showed that APS greatly improved the clinical symptoms, lung damage, reduced the virus loads, and mortality rate of the infected mice.
