A Esfandiari, B Pourghassem Gargari, H Noshad 3, P Sarbakhsh 4, M Mobasseri, M Barzegari, and P Arzhang
Researchers found an association between vitamin D deficiency and diabetic nephropathy. Because of this, a study examined the effects of Vitamin D3 on metabolic and inflammatory parameters in patients with diabetic nephropathy. The trial, randomized, double-blind, placebo-controlled, consisted on 50 patients diagnosed diabetic nephropathy for an eight-week period. The patients were randomly put into two different groups—intervention and placebo; and next received a vitamin D3 (50,000 IU) supplement weekly on a certain day. The study reported drastic differences between the intervention and placebo groups. Researchers concluded that vitamin D supplementation may be an effective way to prevent the progression of diabetic nephropathy.